Nucleohistone dissociation by ganglioside micelles.
نویسندگان
چکیده
The sialic acid-containing glycosphingolipids known as gangliosides can reverse the heat stabilization of DNA by histones. The ability of pure mono-and disialogangliosides to dissociate reconstituted nucleohistone is directly dependent on their sialic acid content; they are effective in concenitrations above their critical micelle concentration.
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ورودعنوان ژورنال:
- Science
دوره 154 3751 شماره
صفحات -
تاریخ انتشار 1966